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Balancing her creative writing, Katie is a bead artist whose jewelry is available for sale at etsy. Find one-of-a-kind bargains at her etsy shop: Are you an author? Help us improve our Author Pages by updating your bibliography and submitting a new or current image and biography. Learn more at Author Central. Popularity Popularity Featured Price: Low to High Price: High to Low Avg. The Somebody Who Jun 13, Available for download now. Only 1 left in stock more on the way.
Martin Lost and Found Apr 03, The pivotal role of astrocytes in the metabolism of iron in the brain. Upregulation of iron regulatory proteins and divalent metal transporter-1 isoforms in the rat hippocampus after kainate induced neuronal injury. Transferrin receptor on endothelium of brain capillaries. The role of iron in neurodegeneration. Milardi D, Rizzarelli E, editors. Heterogenous distribution of ferroportin-containing neurons in mouse brain. Developmental iron uptake and axonal transport in the retina of the rat. Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2.
Astrocyte-endothelial interactions at the blood-brain barrier. Xu J, Ling EA. Studies of the ultrastructure and permeability of the blood-brain barrier in the developing corpus callosum in postnatal rat brain using electron dense tracers. Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier.
Cellular distribution of transferrin, ferritin, and iron in normal and aged human brains. Relationship of iron to oligodendrocytes and myelination. J Wiley and Son; Cellular management of iron in the brain. The IL and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells.
Microglia in the aging brain. J Neuropathol Exp Neurol. Iron accumulation during cellular senescence. Ann N Y Acad Sci. Pathogenic implications of iron accumulation in multiple sclerosis. Impaired iron status in aging research. Int J Mol Sci.
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Iron levels in the human brain: J Trace Elem Med Biol. Brain trace elements and aging.
Interaction of Neuromelanin and iron in substantia nigra and other areas of human brain. The determination of iron and other metals by INAA in cortex, cerebellum and putamen of human brain and in their neuromelanins. J Radioanal Nucl Chem. Brain ferritin iron may influence age- and gender-related risks of neurodegeneration. Age-related iron deposition in the basal ganglia: Gender and iron genes may modify associations between brain iron and memory in healthy aging. MRI estimates of brain iron concentration in normal aging using quantitative susceptibility mapping. Neuromelanin and iron in human locus coeruleus and substantia nigra during aging: New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals.
Heme oxygenase-1 and neurodegeneration: Oxidative DNA damage and nucleotide excision repair. Protein carbonylation in human diseases.
Mitochondrial iron metabolism and its role in neurodegeneration. Catechol oxidation by peroxidase-positive astrocytes in primary culture: Sulzer D, Zecca L. Dopamine-dependent iron toxicity in cells derived from rat hypothalamus. Iron-mediated bioactivation of 1-methylphenyl-1,2,3,6-tetrahydropyridine MPTP in glial cultures. Metallobiology of 1-methylphenyl-1,2,3,6-tetrahydropyridine neurotoxicity.
Iron III induces aggregation of hyperphosphorylated tau and its reduction to iron II reverses the aggregation: Liu Y, Connor JR. Iron and ER stress in neurodegenerative disease. Mitochondria, oxidative stress and cell death. Free Radic Biol Med. Altamura S, Muckenthaler MU. Iron toxicity in diseases of aging: Implication of the proprotein convertases in iron homeostasis: Silvestri L, Camaschella C.
J Cell Mol Med. A synthetic peptide with the putative iron binding motif of amyloid precursor protein APP does not catalytically oxidize iron. The amyloid precursor protein APP does not have a ferroxidase site in its E2 domain. Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export. Magnetic resonance imaging of brain iron. Imaging iron stores in the brain using magnetic resonance imaging.
High-field MRI of single histological slices using an inductively coupled, self-resonant microcoil: Role of brain iron accumulation in cognitive dysfunction: Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.
Long-term overexpression of heme oxygenase 1 promotes tau aggregation in mouse brain by inducing tau phosphorylation. Expression of heme oxygenase-1 in the senescent and Alzheimer-diseased brain. Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment. Increased nigral iron content in postmortem parkinsonian brain. Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains. Blood-brain barrier dysfunction in parkinsonian midbrain in vivo.
Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease. Aggregation and neurotoxicity of alpha-synuclein and related peptides. Metal-triggered structural transformations, aggregation, and fibrillation of human alphasynuclein. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopy. Iron-melanin complex in substantia nigra of parkinsonian brains: Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methylphenyl-1,2,3,6-tetrahydropyridine exposure.
Human Neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: Decreased iron levels in the temporal cortex in postmortem human brains with Parkinson disease. A different marker profile in four neurodegenerative diseases. Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury.
Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease. Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease. Serum iron levels and the risk of Parkinson disease: Anemia or low hemoglobin levels preceding Parkinson disease: Midbrain iron content in early Parkinson disease: Magn Reson Med Sci. Basics, technique and clinical applications. In vivo detection of iron and Neuromelanin by transcranial sonography: Degeneration of nigrostriatal dopaminergic neurons increases iron within the substantia nigra: Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis.
MRI assessment of iron deposition in multiple sclerosis. J Magn Reson Imaging. Quantitative in vivo magnetic resonance imaging of multiple sclerosis at 7 Tesla with sensitivity to iron. Tracking iron in multiple sclerosis: Chronic multiple sclerosis lesions: Proinflammatory cytokines promote glial heme oxygenase-1 expression and mitochondrial iron deposition: Ye H, Rouault TA. Human iron-sulfur cluster assembly, cellular iron homeostasis, and disease. Current concepts and controversies in neurodegeneration with brain iron accumulation.
Neurodegeneration with brain iron accumulation—clinical syndromes and neuroimaging. Iron metabolism in the CNS: Dusek P, Schneider SA. Neurodegeneration with brain iron accumulation. Gregory A, Hayflick SJ. Genetics of neurodegeneration with brain iron accumulation. Curr Neurol Neurosci Rep. Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegeneration.
Neuroimaging features of neurodegeneration with brain iron accumulation. PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron. Anatomy of the pons. Cerebellopontine angle Superior medullary velum Sulcus limitans Medial eminence Facial colliculus. Trapezoid body Trigeminal lemniscus Dorsal trigeminal tract Ventral trigeminal tract Medial lemniscus Lateral lemniscus Medial longitudinal fasciculus Vestibulo-oculomotor fibers Anterior trigeminothalamic tract Central tegmental tract.
Inferior cerebellar peduncle Vestibulocerebellar tract Medial longitudinal fasciculus Vestibulospinal tract Medial vestibulospinal tract Lateral vestibulospinal tract. Trigeminal motor nucleus Facial motor nucleus GSE: Superior salivary nucleus Inferior salivary nucleus. Apneustic center Pneumotaxic center Parabrachial nuclei Subparabrachial nucleus Medial parabrachial nucleus Lateral parabrachial nucleus Superior olivary nucleus Locus coeruleus. Anatomy of the midbrain. Inferior colliculus Brachium Superior colliculus Brachium. Spinotectal tract Central tegmental tract. Periaqueductal gray Raphe nuclei dorsal.
Ventral tegmental area Rostromedial tegmental nucleus Pedunculopontine nucleus. Red nucleus Rostral interstitial nucleus of medial longitudinal fasciculus Parabrachial area. Interpeduncular nucleus Midbrain reticular formation. Pars compacta Pars reticulata. Superior cerebellar peduncle Decussation Interpeduncular fossa. Anatomy of the cerebellum. Dentate interposed Emboliform Globose Fastigial. Mossy fibers Climbing fiber Parallel fiber. Dorsal spinocerebellar tract Olivocerebellar tract Cuneocerebellar tract Juxtarestiform body Vestibulocerebellar tract Trigeminocerebellar fibers Middle pons: Pontocerebellar fibers Superior midbrain: Ventral spinocerebellar tract Dentatothalamic tract.
Anatomy of the diencephalon of the human brain. Pineal gland Habenula Habenular trigone Habenular commissure. Pretectal area Habenular nuclei Subcommissural organ. Stria medullaris of thalamus Thalamic reticular nucleus Taenia thalami. Mammillothalamic tract Pallidothalamic tracts Ansa lenticularis Lenticular fasciculus Thalamic fasciculus PCML Medial lemniscus Trigeminal lemniscus Spinothalamic tract Lateral lemniscus Dentatothalamic tract Acoustic radiation Optic radiation Subthalamic fasciculus Anterior trigeminothalamic tract Medullary laminae.
Posterior is diencephalon, but anterior is glandular. Subthalamic nucleus Zona incerta Nuclei campi perizonalis Fields of Forel. Commissural fibers in the human brain. Vascular organ of lamina terminalis Anterior commissure.
Septal nuclei Medial septal nucleus Subfornical organ Cave of septum pellucidum. Rostral basal ganglia of the human brain and associated structures. Thalamic fasciculus Ansa lenticularis Lenticular fasciculus Subthalamic fasciculus. Anterior olfactory nucleus Anterior perforated substance Olfactory bulb. Olfactory tract Medial olfactory stria Lateral olfactory stria Olfactory trigone. Substantia innominata Nucleus basalis Nucleus of diagonal band. Diagonal band of Broca Stria terminalis. Alveus Fimbria Perforant path Schaffer collateral.