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However, this technique was limited to evaluation of proximal and middle segments only. In this study a total of of proximal and middle segments of coronary arteries were interpretable.
The results were compared with conventional coronary angiography. The low sensitivity with 3D coronary MRA was attributed to inadequate synchronization during the end-expiration phase [ 38 ]. Magnetic resonance imaging has technical limitations that make it more challenging for plaque volume measurements, but it has great potential for noninvasive quality assessment, using a variety of sequencing techniques eg, T1, T2, fat saturation [ 39 , 40 ]. In addition to being used to research study atherosclerotic plaques in the human carotids and aorta [ 41 ], MR appears particularly promising for identifying vulnerable coronary plaques [ 42 ].
Coronary arteries are relatively deeply located and create motion artifact, but in a study using a porcine model of CAD, MR imaging was found to sufficiently differentiate among fibrocellular, lipid-rich, and calcified coronary plaques, and its findings correlated with histopathologic findings [ 43 ]. For more precise quantification, contrast agents that target specific molecules eg, adhesion molecules or other substances are being developed [ 44 , 45 ].
In animal models, MR has also been a powerful tool in serially investigating in vivo the progression and regression of atherosclerotic lesions [ 46 ]. Given the rapid development of this field, the ability to identify, aggressively treat, and serially monitor patients with high-risk plaques will probably improve significantly in the near future. Despite existing limitations, there is an important segment of the population in whom noninvasive imaging could provide coronary anatomic information with sufficient diagnostic quality.
Furthermore, various noninvasive techniques offer potential advantages over traditional invasive coronary angiography, such as characterizing coronary plaque, providing both structural and functional information about the left ventricle and heart valves, and not exposing patients to the risk of vascular injury. On the horizon, combined CT and MR imaging may provide information not available from other imaging modalities, including lesion localization along with structural and biological plaque characterization.
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Abstract Noninvasive coronary angiography has become an important imaging tool in the evaluation of patients with and at risk for coronary artery disease CAD. Coronary angiography, cardiac computed tomography, magnetic resonance imaging. Open in a separate window. Computed Tomographic Angiography of the Coronary Arteries. Specific Indications Widespread use of MDCT in broad clinical populations without specific indications can lead to further unnecessary testing and escalating costs [ 21 ].
Cardiac Allograft Vasculopathy Because noninvasive functional tests have traditionally lacked adequate sensitivity and specificity, conventional coronary angiography is the current gold standard for the serial detection and follow-up of cardiac allograft vasculopathy in heart transplant patients. Computed Tomography Scans for the Assessment of Chest Pain in the Emergency Department The possibility of using MDCT for comprehensive assessment of cardiac and noncardiac causes of chest pain in patients presenting to the emergency room is being evaluated.
Magnetic Resonance Angiography of the Coronary Arteries. Eur Radiol ; Plaque Characterization Magnetic resonance imaging has technical limitations that make it more challenging for plaque volume measurements, but it has great potential for noninvasive quality assessment, using a variety of sequencing techniques eg, T1, T2, fat saturation [ 39 , 40 ].
Invasive evaluation coronary arteriography of the coronary artery disease patient: The coronary angiogram and its seminal contributions to cardiovascular medicine over five decades. The complications of coronary arteriography. Complications associated with cardiac catheterisation and angiography. Noninvasive coronary angiography using computed tomography - Ready to kick it up another notch? Noninvasive coronary imaging and assessment of left ventricular function using slice computed tomography.
Multidetector computed tomography for the diagnosis of coronary artery disease: Accuracy of MSCT coronary angiography with slice technology: J Am Coll Cardiol. Accuracy of row multidetector computed tomography for the assessment of coronary artery stenosis. Non-invasive detection of coronary artery disease in patients with left bundle branch block using slice computed tomography. Accuracy of thin-slice computed tomography in the detection of coronary stenoses.
Lesions in the left main coronary artery in patients with three vessel disease could be identified with some certainty in a limited number of patients. Accuracy of thin-slice computed tomography in the detection of coronary stenoses. Once used primarily as research tools, these modalities are increasingly being used in routine clinical practice, particularly for direct imaging of the coronary vasculature. Clinical Arrhythmology and Electrophysiology: Finally, intravenous contrast and radiation limit the use of MDCT.
Estimating risk of cancer associated with radiation exposure from slice computed tomography coronary angiography. Step-and-shoot data acquisition and reconstruction for cardiac x-ray computed tomography. Cardiac imaging using detector row four-dimensional CT: Clinical potentials of the prototype detector row CT-scanner. Volumetric coronary angiography using the detector row computed tomography scanner: Initial evaluation of coronary images from detector row computed tomography. Int J Cardiovasc Imaging.
Cardiovascular CT and MR Imaging: From Technique to Clinical part and provide an approach to the diagnostic interpretation of disease. Cardiovascular CT and MR Imaging. From Technique to Clinical Interpretation. Editors: Catalano, Carlo, Anzidei, Michele, Napoli, Alessandro (Eds.) The book.
Systematic review of the clinical effectiveness and cost-effectiveness of slice or higher computed tomography angiography as an alternative to invasive coronary angiography in the investigation of coronary artery disease. The utilization of cardiac imaging. Coronary calcium independently predicts incident premature coronary heart disease over measured cardiovascular risk factors: Noninvasive visualization of coronary artery bypass grafts using detector row computed tomography.
Coronary stenosis detection by slice computed tomography in heart transplant patients: Chest pain evaluation in the emergency department: A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain. Usefulness of slice cardiac computed tomographic angiography for diagnosing acute coronary syndromes and predicting clinical outcome in emergency department patients with chest pain of uncertain origin. Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography: Detection of plaque rupture using slice multidetector row computed tomography.
Assessment of changes in non-calcified atherosclerotic plaque volume in the left main and left anterior descending coronary arteries over time by slice computed tomography. Characterization of atherosclerotic plaques in human coronary arteries with slice multidetector row computed tomography by analysis of attenuation profiles. Assessment of coronary arteries with total study time of less than 30 minutes by using whole-heart coronary MR angiography.
Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging. Coronary magnetic resonance angiography for the detection of coronary stenosis. N Engl J Med. Intraindividual comparison of contrast-enhanced electron-beam computed tomography and navigator-echo-based magnetic resonance imaging for noninvasive coronary artery angiography.
Effects of aggressive versus conventional lipid-lowering therapy by simvastatin on human atherosclerotic lesions: Effects of lipid-lowering by simvastatin on human atherosclerotic lesions: Computed tomography and magnetic resonance imaging for noninvasive coronary angiography and plaque imaging: Fuster V, Kim RJ. Frontiers in cardiovascular magnetic resonance. Noninvasive in vivo magnetic resonance imaging of experimental coronary artery lesions in a porcine model. Jaffer FA, Weissleder R. Lipid-rich atherosclerotic plaques detected by gadofluorine-enhanced in vivo magnetic resonance imaging.
Progression and regression of atherosclerotic lesions: Support Center Support Center. Content Types A limited number of items are shown. Click to view More Electronic books.
Physical Details 1 online resource p. Summary The availability and diffusion of high-performance technologies has strengthened the role of CT angiography and MR angiography as simple, reliable techniques for the characterization and treatment planning of the principal diseases of the cardiovascular system, an understanding of which has become essential for all radiologists. The aim of this book is to provide concise but thorough information and guidance on the main methods and examination techniques used when performing high-quality CT angiography and MR angiography studies in a broad range of clinical settings.
The lucid text is supported by a large number of case studies and is rich in advice on image interpretation and practical suggestions for the evaluation and reporting of the examinations. Importantly, a central feature is detailed comparison of the advantages and limitations of the two techniques in various diseases and vascular regions; the book will therefore enable both trainee and expert radiologists to understand their indications and to select the most appropriate technique in different contexts. Notes Description based upon print version of record.
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